My research interests concern the molecular epidemiology of bacterial pathogens - in particular Neisseria meningitidis and Streptococcus pneumoniae. I am currently using deterministic models to investigate the effects of immune selection and ecological competition on strain structure, with an aim to incorporate virulence genes into the framework. I am also interested in invasive meningococcal disease in Sub-Saharan Africa, which experiences the highest rates of disease in the world, with large epidemics every 8-10 years. I hope to use theoretical frameworks in conjunction with laboratory methods to investigate the strain structure of N. meningitidis in this region.
Tel: +44 (0) 1865 281309
- Buckee CO, Recker M, Watkins ER, Gupta S (2011) Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations. Proceedings of the National Academy of Sciences USA. 108(37):15504-9.